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ACGIH 11-009

2010 Edition, January 1, 2010

Complete Document

Principles and Practice of Mixtures Toxicology



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Description / Abstract:

Providing the latest research in nanoparticle toxicology, this comprehensive and practical book addresses all areas where toxic mixtures are encountered including environmental, occupational, and medical settings. Special consideration is given to air and water and to specific requirements for study design in mixture toxicology. Topics covered include:
  • Mixtures toxicology and risk assessment
  • Exposure assessment and biomonitoring
  • Relative potency factor approach
  • Statistical methods and techniques
  • Pharmacokinetics and pharmacodynamics interactions
  • Hazardous waste sites, workplace exposures, drug combinations, water disinfection by-products, endocrine active chemicals, food ingredients
  • Dermal toxicity
  • Polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and nanoparticles


Practice-oriented case studies and examples in the second part of the book provide an ideal learning tool for students or a refresher for professionals.