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ASTM E1811

1996 Edition, May 10, 1996

Complete Document

Standard Test Method for Oncogenicity Study in Rats and Mice

Includes all amendments and changes through Editorial Change 1, November 2005

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Product Details:

  • Revision: 1996 Edition, May 10, 1996
  • Published Date: November 2005
  • Status: Not Active, See comments below
  • Document Language: English
  • Published By: ASTM International (ASTM)
  • Page Count: 4
  • ANSI Approved: No
  • DoD Adopted: No

Description / Abstract:

This test method covers a long-term study to determine the oncogenicity potential of a substance in mammalian species such as the rat and mouse. The objective is to observe the test animals for a major portion of their life span for neoplastic lesions during exposure to various doses of a test substance by oral administration.

This test may also provide some information on long-term general toxicity.

This test method assumes that the user is knowledgeable in mammalian toxicology and related pertinent areas, and it relies heavily on the judgment of the evaluator.

The values stated in SI units are to be regarded as the standard. The values given in parentheses are for information only.

This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use. Specific hazards statements are given in Section 6.