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Head Injury Pathophysiology & Management

2nd Edition, April 29, 2005

Complete Document

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Active, Most Current

Additional Comments:
ISBN: 978-0-340-80724-8
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Product Details:

  • Revision: 2nd Edition, April 29, 2005
  • Published Date: April 29, 2005
  • Status: Active, Most Current
  • Document Language: English
  • Published By: CRC Press (CRC)
  • Page Count: 520
  • ANSI Approved: No
  • DoD Adopted: No

Description / Abstract:

Preface to the second edition

TBI continues to be a major problem worldwide. Fatalities from head injuries from motor vehicle accidents are increasing, particularly in developing countries, and are predicted to become the third largest cause of death by 2010. In the United States alone, over 3.5 million disabled head injury survivors exist in the community. Sadly, penetrating brain injury remains an increasing problem in many communities as a result of urban violence and armed conflict.

In the 1950's, over 80% of patients with severe head injuries died as a result of their injuries. In the twenty-first century, mortality rates of around 25% are commonly reported.

Since the first edition in 1997 there have been substantial advances in the understanding of the pathophysiology of severe brain injury derived from laboratory models and clinical studies. A clearer understanding of the events which occur in the minutes to hours following brain injury lead to the development of a number of agents with neuroprotective effects in laboratory models. The search for ways to apply this knowledge continues.

The development and wide application of guidelines for management of all types of head injury and the wider availability of rapid prehospital care, CT scans, and intensive care units has set generally accepted standards of management, although there remain many areas of controversy.

This edition of the book incorporates the latest evidencebased US guidelines on severe head injury management, and surgical management of TBI.However, these guidelines do not take account of the enormous body of knowledge from animal models, and ‘expert opinion'.

This book aims to provide the reader with a conceptual framework, and detailed synthesis of the mechanisms of brain damage in TBI, and then integrates imaging, management and the functional consequences. We have therefore divided the book into three parts – mechanisms of injury, measuring and monitoring the injury, and treatment for the injury.

There are new chapters on penetrating injuries, pediatric brain injury and outcome measures and brain death. Appendices detail management algorithms.

This second edition is designed mainly to assist neurosurgeons, trauma surgeons and intensivists managing patients with severe traumatic brain injury, but we hope it will provide an integrated reference framework for researchers, and all the many other diverse groups of physicians and scientists, who come into this field.