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Pharmacotherapy of Cachexia

2005 Edition, December 22, 2005

Complete Document

Detail Summary

Active, Most Current

Additional Comments:
ISBN: 978-0-8493-3379-8
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Product Details:

  • Revision: 2005 Edition, December 22, 2005
  • Published Date: December 22, 2005
  • Status: Active, Most Current
  • Document Language: English
  • Published By: CRC Press (CRC)
  • Page Count: 608
  • ANSI Approved: No
  • DoD Adopted: No

Description / Abstract:


Cachexia is an underestimated and frequently neglected medical condition. Although it is regarded as an independent risk factor for morbidity and mortality it does not receive sufficient medical attention and treatment. The therapy of cachexia requires a coordinated, flexible, and multidisciplinary approach. Since neither nutritional therapy nor physical exercise is sufficient to treat cachexia, pharmacotherapy plays an important role. A wide variety of drugs with highly diverse mechanisms of action is currently being used but for many of them convincing evidence of therapeutic efficacy is lacking and their benefit/risk ratio is unknown.

The present book was conceived with the aim of providing a comprehensive reference source for health care professionals concerned with the treatment of cachexia. It is organized in six sections; the first one dealing with the pathophysiology of cachexia, the second with the diseases associated with cachexia, and the third with general therapeutic aspects. The subsequent three sections are devoted to pharmacotherapy. A section on drugs in clinical use is followed by one on drugs in research and development and a final section, which is focused on future developments.

Why should a reader interested in cachexia consult a book instead of reading the latest reviews or research articles? The editors strongly believe that a heterogeneous syndrome such as cachexia and its diverse treatment options can be best presented in a single volume where contributions by different authors on various aspects can be found and compared. Such a broad range of chapters allows the reader to find information about various different aspects of the disease and its treatment and to select the most pertinent aspects relating to his specific question by using a single reference source.

We are grateful to the numerous internationally recognized specialists who have contributed chapters on various aspects of cachexia. Through their critical evaluation of pathophysiological mechanisms, clinical features, and therapeutic options this book provides the reader with a valuable source of information on all aspects of this serious and life-threatening syndrome.We would also like to thank the publishers for their expert editorial advice and particularly acknowledge the excellent support of Jny Wittker who was responsible for all administrative and organizational work throughout the preparation of this volume.